IN VIVO INCORPORATION OF GLUCOSE CARBON INTO BRAIN AND LIVER PROTEINS IN BIOTIN-DEFICIENT RATS

IN VIVO INCORPORATION OF GLUCOSE CARBON INTO BRAIN AND LIVER PROTEINS IN BIOTIN-DEFICIENT RATS

The in vivo utilization of D-[U-14C] glucose with particular reference to its incorporation into brain and liver proteins was studied in biotin-deficient rats. The data show a significant reduction in the incorporation of glucose carbon into brain and liver proteins. A disturbance in the intermediar...

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Veröffentlicht in:Journal of Nutritional Science and Vitaminology 1976, Vol.22(2), pp.79-87
Hauptverfasser: BHAGAVAN, Hemmige N., COURSIN, David B.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Biotin - deficiency
Body Weight
Brain - metabolism
Glucose - metabolism
Liver - metabolism
Male
Nerve Tissue Proteins - biosynthesis
Protein Biosynthesis
Rats
Time Factors
Vitamin B Deficiency - metabolism
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Zusammenfassung:The in vivo utilization of D-[U-14C] glucose with particular reference to its incorporation into brain and liver proteins was studied in biotin-deficient rats. The data show a significant reduction in the incorporation of glucose carbon into brain and liver proteins. A disturbance in the intermediary metabolism of glucose appears to be one of the factors responsible for the decreased incorporation of the label into proteins in biotin deficiency.
ISSN:0301-4800
1881-7742
DOI:10.3177/jnsv.22.79