Role of ischemia in the induction of changes in cell membrane during hemorrhagic shock

Role of ischemia in the induction of changes in cell membrane during hemorrhagic shock

Sustained hemorrhagic shock results in consistent depression of the transmembrane potential difference in the skeletal muscle cell. Ischemia produces abrupt changes in the PD after a variable but long period of electrogenic normality. In the presence of shock, a tourniquet isolated extremity would s...

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Veröffentlicht in:The Journal of surgical research 1976-05, Vol.20 (5), p.473-476
Hauptverfasser: Arango, Abelardo, Illner, Hana, Shires, G.Tom
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Cell Membrane - physiology
Dogs
Hemodynamics
Hindlimb
Ischemia - physiopathology
Membrane Potentials
Muscles - blood supply
Muscles - physiopathology
Shock, Hemorrhagic - physiopathology
Tourniquets
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Zusammenfassung:Sustained hemorrhagic shock results in consistent depression of the transmembrane potential difference in the skeletal muscle cell. Ischemia produces abrupt changes in the PD after a variable but long period of electrogenic normality. In the presence of shock, a tourniquet isolated extremity would show the changes of ischemia, but not those of shock. The PD changes seen during hemorrhagic shock appear not primarily related to tissue ischemia.
ISSN:0022-4804
1095-8673
DOI:10.1016/0022-4804(76)90122-0