Effect of Lymphocyte Depletion by Thoracic Duct Fistula and Administration of Antilymphocytic Serum on the Survival of Skin Homografts in Rats

Effect of Lymphocyte Depletion by Thoracic Duct Fistula and Administration of Antilymphocytic Serum on the Survival of Skin Homografts in Rats

SINCE lymphocytes appear to play a crucial part in the homograft reaction it seemed of interest to examine the behaviour of homografts in recipients subjected to chronic lymphocyte depletion by: ( a ) drainage of lymph through a thoracic duct fistula; ( b ) repeated administration of a hetero-specif...

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Veröffentlicht in:Nature (London) 1963-11, Vol.200 (4907), p.702-702
Hauptverfasser: WOODRUFF, M. F. A., ANDERSON, N. A.
Format: Artikel
Sprache:eng
Schlagworte:
Allografts
Fistula
Humanities and Social Sciences
Immune Sera
letter
Leukopenia
Lymphocyte Depletion
Lymphocytes
multidisciplinary
Old Medline
Rats
Science
Science (multidisciplinary)
Skin Transplantation
Thoracic Duct
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Zusammenfassung:SINCE lymphocytes appear to play a crucial part in the homograft reaction it seemed of interest to examine the behaviour of homografts in recipients subjected to chronic lymphocyte depletion by: ( a ) drainage of lymph through a thoracic duct fistula; ( b ) repeated administration of a hetero-specific antilymphocytic serum; ( c ) a combination of these procedures.
ISSN:0028-0836
1476-4687
DOI:10.1038/200702a0