Pyridazines. V. The Reaction of Methyl Substituted 4-Nitropyridazine 1-Oxides with Acetyl Chloride
Reaction of excess acetyl chloride on a 3-substituted 4-nitro-6-methylpyridazine 1-oxide (Ia, b, c and XIII) result in the formation of 3-substituted 4-chloro-6-formylpyridazine 1-oxide oximes (IIa, b, c and XVIII), together with 3-substituted 4-chloro-6-methylpyridazine 1-oxides (IIa, b, c and XVII...
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Veröffentlicht in: | Chemical & pharmaceutical bulletin 1963/12/25, Vol.11(12), pp.1511-1516 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Reaction of excess acetyl chloride on a 3-substituted 4-nitro-6-methylpyridazine 1-oxide (Ia, b, c and XIII) result in the formation of 3-substituted 4-chloro-6-formylpyridazine 1-oxide oximes (IIa, b, c and XVIII), together with 3-substituted 4-chloro-6-methylpyridazine 1-oxides (IIa, b, c and XVII). Reaction of 3-methyl-4-nitropyridazine 1-oxide (XII) and 4-nitro-5-methylpyridazine 1-oxide (XIV) with acetyl chloride gave only 3-methyl-4-chloropyridazine 1-oxide (XIII) and 4-chloro-5-methylpyridazine 1-oxide (XV) respectively. |
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ISSN: | 0009-2363 1347-5223 |
DOI: | 10.1248/cpb.11.1511 |