EFFECTS OF URSODESOXYCHOLIC ACID ON THE AMOUNT OF URINARY THIAMINE AND RIBOFLAVIN FROM PATIENTS WITH PULMONARY TUBERCULOSIS

1. Abnormal excretion of thiamine and riboflavin from the patients with pulmonary tuberculosis was not ascertained in this study. 2. More reduction of urinary thiamine and riboflavin by administration of UDCA was observed after loading the vitamins to the patients than without loading. 3. Administration of UDCA for a long period of time did not improve the liver function of the patients with tuberculosis to absorb the vitamins. 4. Reduction of the amounts of excreted thiamine and riboflavin after administration of UDCA was supposed to be due to the increase of phosphorylation and absorption of both vitamins.