The occurrence and identification of o-hydroxyhippuric acid (salicyluric acid) in the urine of sick children

The occurrence and identification of o-hydroxyhippuric acid (salicyluric acid) in the urine of sick children

o-Hydroxyhippuric acid has been identified in the urine of a number of sick children who were not receiving salicylate-containing drugs. Characterisation was effected by thin-layer and gas-liquid chromatography and by gas-liquid chromatography-mass spectrometry. An association between gastro-intesti...

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Veröffentlicht in:Clinica chimica acta 1976-07, Vol.70 (1), p.171-178
Hauptverfasser: Finnie, M.D.A., Ersser, R.S., Seakins, J.W.T., Snedden, W.
Format: Artikel
Sprache:eng
Schlagworte:
Child
Chromatography, Gas - methods
Chromatography, Thin Layer - methods
Gas Chromatography-Mass Spectrometry - methods
Gastrointestinal Diseases - urine
Hippurates - urine
Humans
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Zusammenfassung:o-Hydroxyhippuric acid has been identified in the urine of a number of sick children who were not receiving salicylate-containing drugs. Characterisation was effected by thin-layer and gas-liquid chromatography and by gas-liquid chromatography-mass spectrometry. An association between gastro-intestinal dysfunction and the excretion of o-hydroxyhippuric acid was observed in approximately 50% of the patients who excreted this substance.
ISSN:0009-8981
1873-3492
DOI:10.1016/0009-8981(76)90020-6