Sphingolipid Antibodies. II. Specificity of Antibody in Patients with Demyelinating Diseases.

Sphingolipid Antibodies. II. Specificity of Antibody in Patients with Demyelinating Diseases.

Summary Five human patients' sera containing antiganglioside activity were examined with various ganglioside preparations utilizing hemagglutination and hemagglutination inhibition techniques. The results indicate that the activity in these cases is specific for monosialoganglioside.

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Veröffentlicht in:Experimental biology and medicine (Maywood, N.J.) N.J.), 1963-11, Vol.114 (2), p.350-352
Hauptverfasser: Somers, John E., Kanfer, Julian N., Brady, Roscoe O.
Format: Artikel
Sprache:eng
Schlagworte:
Amyotrophic Lateral Sclerosis
Antibodies
Demyelinating Diseases
Gangliosides
Hemagglutination
Hemagglutination Inhibition Tests
Hemagglutination Tests
Humans
Immunoglobulins
Lipid Metabolism
Lipidoses
Lipids
Multiple Sclerosis
Neuraminic Acids
Old Medline
Sphingolipids
Tay-Sachs Disease
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Zusammenfassung:Summary Five human patients' sera containing antiganglioside activity were examined with various ganglioside preparations utilizing hemagglutination and hemagglutination inhibition techniques. The results indicate that the activity in these cases is specific for monosialoganglioside.
ISSN:0037-9727
1535-3702
1535-3699
DOI:10.3181/00379727-114-28673