Practical considerations in the development of a human cancer vaccine

Practical considerations in the development of a human cancer vaccine

Factors involved in the development of a human oncornavirus vaccine are discussed. The isolation and purification of subviral gp69/71 antigenic components enhance the feasibility of developing safe vaccine. The recent isolation of a C-type virus (the HL-23) from a human leukemic patient and its simi...

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Veröffentlicht in:Cancer research (Chicago, Ill.) Ill.), 1976-02, Vol.36 (2 pt 2), p.861-864
Hauptverfasser: Mayyasi, S A, Larson, D L, Ahmed, M
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Humans
Neoplasms - prevention & control
Viral Proteins - analysis
Viral Vaccines
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Zusammenfassung:Factors involved in the development of a human oncornavirus vaccine are discussed. The isolation and purification of subviral gp69/71 antigenic components enhance the feasibility of developing safe vaccine. The recent isolation of a C-type virus (the HL-23) from a human leukemic patient and its similarity to the simian sarcoma virus presents us with a unique opportunity to test the safety and potency of a vaccine in nonhuman primates.
ISSN:0008-5472