Lactate Dehydrogenase Variant from Human Blood: Evidence for Molecular Subunits

Lactate Dehydrogenase Variant from Human Blood: Evidence for Molecular Subunits

A variant of human lactate dehydrogenase is described. The occurrence of lactate dehydrogenase-1, -2, -3, and -4 as five, four, three, and two components, respectively, is interpreted as supporting the hypothesis that LDH isozymes are tetramers formed from various combinations of two types of subuni...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1963-08, Vol.141 (3581), p.642-643
Hauptverfasser: Boyer, Samuel H., Fainer, David C., Watson-Williams, E. J.
Format: Artikel
Sprache:eng
Schlagworte:
Blood
Dehydrogenases
Electrophoresis
Erythrocytes
Gels
Hemoglobins
Humans
Isoenzymes
L-Lactate Dehydrogenase
Lactates
Molecular weight
Old Medline
Reaction kinetics
Starches
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Zusammenfassung:A variant of human lactate dehydrogenase is described. The occurrence of lactate dehydrogenase-1, -2, -3, and -4 as five, four, three, and two components, respectively, is interpreted as supporting the hypothesis that LDH isozymes are tetramers formed from various combinations of two types of subunits.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.141.3581.642