Technetium-99m-Glucoheptonate as a Brain-Scanning Agent: Critical Comparison with Pertechnetate

Delayed 99mTc-glucoheptonate and pertechnetate scans were evaluated in a paired study for their ability to detect brain lesions. Glucoheptonate was found to be superior in eight of 17 cases of brain tumor and in two of ten patients with cerebral infarction. In addition, early (30 min) 99mTc-glucohep...

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Veröffentlicht in:	The Journal of nuclear medicine (1978) 1976-05, Vol.17 (5), p.345-348
Hauptverfasser:	Waxman, Alan D, Tanacescu, Doina, Siemsen, Jan K, Wolfstein, Ralph S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Brain - blood supply Brain Diseases - diagnosis Brain Neoplasms - diagnosis Breast Neoplasms - diagnosis Carcinoma, Bronchogenic - diagnosis Female Humans Infarction - diagnosis Lung Neoplasms - diagnosis Melanoma - diagnosis Neoplasm Metastasis Radionuclide Imaging Skull Neoplasms - diagnosis Sugar Acids Technetium Time Factors Uterine Cervical Neoplasms - diagnosis
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Zusammenfassung:	Delayed 99mTc-glucoheptonate and pertechnetate scans were evaluated in a paired study for their ability to detect brain lesions. Glucoheptonate was found to be superior in eight of 17 cases of brain tumor and in two of ten patients with cerebral infarction. In addition, early (30 min) 99mTc-glucoheptonate brain scans were compared with delayed studies: the former were inferior in 48% of the cases. We conclude that 99mTc-glucoheptonate is a promising agent for delayed brain scanning, offering better lesion detection than pertechnetate.
ISSN:	0161-5505 1535-5667