Isolation of flindersiamine, isoflindersiamine, and a new alkaloid, heliparvifoline, from helietta parvifolia (rutaceae)

A phytochemical investigation of the leaves and twigs of Helietta parvifolia (Rutaceae) resulted in the isolation of heliparvifoline, a new furoquinoline alkaloid, in addition to the known bases flindersiamine and isoflindersiamine.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of pharmaceutical sciences 1976-04, Vol.65 (4), p.561-563
Hauptverfasser:	Chang, P.T.O., Aynilian, G.H., Cordell, G.A., Tin‐Wa, M., Fong, H.H.S., Perdue, R.E., Farnsworth, N.R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaloids - isolation & purification Alkaloids - therapeutic use alkaloids isolated Alkaloids-flindersiamine Alkaloids—flindersiamine, isoflindersiamine, and heliparvifoline isolated from Helietta parvifolia leaves and twigs, cytotoxicity evaluated and heliparvifoline isolated from Helietta parvifolia leaves and twigs Animals Antineoplastic Agents - therapeutic use Chemical Phenomena Chemistry Chromatography, Thin Layer cytotoxicity evaluated Cytotoxicity-alkaloids from leaves and twigs of Helietta parvifolia isolated Cytotoxicity—alkaloids from leaves and twigs of Helietta parvifolia isolated, evaluated evaluated Helietta parvifolia-leaves and twigs Helietta parvifolia—leaves and twigs, alkaloids isolated, cytotoxicity evaluated Hydroxyquinolines - isolation & purification Hydroxyquinolines - therapeutic use isoflindersiamine Leukemia, Experimental - drug therapy Mice Neoplasms, Experimental - drug therapy Plants - analysis Quinolines - isolation & purification Quinolines - therapeutic use
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Beschreibung
Zusammenfassung:	A phytochemical investigation of the leaves and twigs of Helietta parvifolia (Rutaceae) resulted in the isolation of heliparvifoline, a new furoquinoline alkaloid, in addition to the known bases flindersiamine and isoflindersiamine.
ISSN:	0022-3549 1520-6017
DOI:	10.1002/jps.2600650420