Stress-Induced Hyperphagia and Obesity in Rats: A Possible Model for Understanding Human Obesity

Stress-Induced Hyperphagia and Obesity in Rats: A Possible Model for Understanding Human Obesity

Mild tail pinch administered to rats several times daily in the presence of sweetened milk induced immediate hyperphagia and led to considerable gain in body weight. Parallels are drawn with stress-induced hyperhagia and altered affective states in obese humans.

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Bibliographische Detailangaben
Veröffentlicht in:Science (American Association for the Advancement of Science) 1976-01, Vol.191 (4224), p.310-312
Hauptverfasser: Rowland, Neil E., Antelman, Seymour M.
Format: Artikel
Sprache:eng
Schlagworte:
Animal grooming
Animal tails
Animals
Axons
Castration
Dopamine - physiology
Estradiol - administration & dosage
Feeding Behavior - physiology
Female
Food
Hyperphagia
Mating behavior
Neurons
Obesity
Obesity - etiology
Rats
Stress, Physiological - complications
Weight gain
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Beschreibung
Zusammenfassung:Mild tail pinch administered to rats several times daily in the presence of sweetened milk induced immediate hyperphagia and led to considerable gain in body weight. Parallels are drawn with stress-induced hyperhagia and altered affective states in obese humans.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.1246617