Phosphorylase a Activity in Uterine Muscle: Stimulation by Ethylenediaminetetraacetic Acid

Phosphorylase a Activity in Uterine Muscle: Stimulation by Ethylenediaminetetraacetic Acid

Injection of ethylenediaminetetraacetic acid into spayed rats or its use in phosphorylase extraction increases the activity of glycogen-phosphorylase a in uterine smooth muscle tissue. Since the total phosphorylase activity is not increased, the increase in phosphorylase a appears to result from a c...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1963-05, Vol.140 (3568), p.811-812
Hauptverfasser: Schane, H. Philip, Leonard, S. L.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Calcium
Edetic Acid
Enzymes
Female
Homogenization
Humans
Muscle, Smooth
Myometrium
Old Medline
Phosphorylase a
Phosphorylases
Phosphotransferases
Rats
Table salt
Uterine tissue
Uterus
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Zusammenfassung:Injection of ethylenediaminetetraacetic acid into spayed rats or its use in phosphorylase extraction increases the activity of glycogen-phosphorylase a in uterine smooth muscle tissue. Since the total phosphorylase activity is not increased, the increase in phosphorylase a appears to result from a conversion of inactive phosphorylase b to the active form of the enzyme.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.140.3568.811