Arylsulphatase a and 2',3'-cyclic nucleotide 3'-phosphohydrolase activities in the brains of myelin deficient mutant mice

Arylsulphatase a and 2',3'-cyclic nucleotide 3'-phosphohydrolase activities in the brains of myelin deficient mutant mice

Arylsulphatase A and 2',3'-cyclic nucleotide 3'-phosphohydrolase activities of myelin deficient mutant mice brains were studied. The results indicated that there were no changes in arylsulphatase A activity of the developing mutant brain, whereas the activity of 2',3'-cyclic...

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Veröffentlicht in:Neuroscience 1976-12, Vol.1 (6), p.519-522
Hauptverfasser: Sarlive, L.L., Farooqui, A.A., Rebel, G., Mandel, P.
Format: Artikel
Sprache:eng
Schlagworte:
2',3'-Cyclic-Nucleotide Phosphodiesterases - metabolism
Age Factors
Animals
Arylsulfatases - metabolism
Brain - enzymology
Brain - growth & development
Brain - physiopathology
Brain Chemistry - genetics
Female
Galactosyltransferases
Ganglioside Galactosyltransferase
Male
Mice
Mice, Neurologic Mutants - metabolism
Myelin Sheath - enzymology
Myelin Sheath - genetics
Psychosine - metabolism
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Zusammenfassung:Arylsulphatase A and 2',3'-cyclic nucleotide 3'-phosphohydrolase activities of myelin deficient mutant mice brains were studied. The results indicated that there were no changes in arylsulphatase A activity of the developing mutant brain, whereas the activity of 2',3'-cyclic nucleotide 3'-phosphohydrolase decreased considerably. The data obtained in this study suggest that in brain arylsulphatase A activity is localized in cells other than oligodendroglia.
ISSN:0306-4522
1873-7544
DOI:10.1016/0306-4522(76)90105-6