Effect of Hypocholesteremic Agents on Protozoa.

Effect of Hypocholesteremic Agents on Protozoa.

Summary The hypocholesteremic agents, triparanol and benzmalecene, inhibit the multiplication of the sterol-synthesizing phytoflagellates, Ochromonas danica, O. malhamensis, Euglena gracilis, and the non-sterol-synthesizing ciliate. Tetrahymena pyriformis. The inhibition of multiplication of the Och...

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Veröffentlicht in:Experimental biology and medicine (Maywood, N.J.) N.J.), 1962-01, Vol.109 (1), p.130-132
Hauptverfasser: Aakonson, S., Bensky, Barbara, Shifrine, M., Baker, Herman
Format: Artikel
Sprache:eng
Schlagworte:
Anticholesteremic Agents
Cholesterol - blood
Eukaryota - pharmacology
Old Medline
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Zusammenfassung:Summary The hypocholesteremic agents, triparanol and benzmalecene, inhibit the multiplication of the sterol-synthesizing phytoflagellates, Ochromonas danica, O. malhamensis, Euglena gracilis, and the non-sterol-synthesizing ciliate. Tetrahymena pyriformis. The inhibition of multiplication of the Ochromonas species may be prevented by cholesterol, ergosterol, farnesol, squalene, lauric acid, oleic acid, linoleic acid, and linolenic acid. Oleic acid and linolenic acid were most effective.
ISSN:0037-9727
1535-3702
1535-3699
DOI:10.3181/00379727-109-27125