Potential Anti-cancer Agents. XII. Synthesis of 4-Azido-3, 6-dimethoxypyridazine Derivatives

Potential Anti-cancer Agents. XII. Synthesis of 4-Azido-3, 6-dimethoxypyridazine Derivatives

4-Azido-3, 6-dimethoxypyridazine (X) was synthesized from 4-chloro-3, 6-dimethoxypyridazine (VII) through the hydrazino compound and X was converted to 4-azido-3, 6-dimethoxypyridazine 1-oxide (XII). Besides, some reactions of 4-chloro-3, 6-dimethoxypyridazine 1-oxide (I) and XII were examined.

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Veröffentlicht in:Chemical & pharmaceutical bulletin 1963/08/25, Vol.11(8), pp.1073-1077
Hauptverfasser: Itai, Takanobu, Kamiya, Shozo
Format: Artikel
Sprache:eng
Schlagworte:
Antineoplastic Agents - chemical synthesis
Pyridazines - chemical synthesis
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Zusammenfassung:4-Azido-3, 6-dimethoxypyridazine (X) was synthesized from 4-chloro-3, 6-dimethoxypyridazine (VII) through the hydrazino compound and X was converted to 4-azido-3, 6-dimethoxypyridazine 1-oxide (XII). Besides, some reactions of 4-chloro-3, 6-dimethoxypyridazine 1-oxide (I) and XII were examined.
ISSN:0009-2363
1347-5223
DOI:10.1248/cpb.11.1073