Mechanism of diuretic response to increased left atrial pressure in the anesthetized dog

Mechanism of diuretic response to increased left atrial pressure in the anesthetized dog. The mechanism whereby an increase in left atrial pressure (LAP) causes a water diuresis in the anesthetized dog remains controversial. In the present study LAP was increased by inflation of an atrial balloon in...

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Veröffentlicht in:Kidney international 1975-12, Vol.8 (6), p.355-361
Hauptverfasser: de Torrente, Antoine, Robertson, Gary L., McDonald, Keith M., Schrier, Robert W., McCool, Abby, Paulsen, Penny, Gilbert, Lowell
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Sprache:eng
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Zusammenfassung:Mechanism of diuretic response to increased left atrial pressure in the anesthetized dog. The mechanism whereby an increase in left atrial pressure (LAP) causes a water diuresis in the anesthetized dog remains controversial. In the present study LAP was increased by inflation of an atrial balloon in two groups of animals. In the first group of eight intact dogs, mean LAP was increased from 3.4 to 17.6mm Hg (P
ISSN:0085-2538
1523-1755
DOI:10.1038/ki.1975.127