Activity of 1-β-D-Arabinofuranosylcytosine Hydrochloride Against Herpes Simplex Keratitis
Summary The antiviral activity of 5-iodo-2′-deoxyuridine in treating herpes simplex keratitis in rabbits was confirmed. Another pyrimidine nucleoside, 1-β-D-arabinofurano-sylcytosine hydrochloride, was found to be at least as effective as IUDR in treating this infection.
Gespeichert in:
| Veröffentlicht in: | Proceedings of the Society for Experimental Biology and Medicine 1962-12, Vol.111 (3), p.660-664 |
|---|---|
| 1. Verfasser: | |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 664 |
|---|---|
| container_issue | 3 |
| container_start_page | 660 |
| container_title | Proceedings of the Society for Experimental Biology and Medicine |
| container_volume | 111 |
| creator | Underwood, Gerald E. |
| description | Summary
The antiviral activity of 5-iodo-2′-deoxyuridine in treating herpes simplex keratitis in rabbits was confirmed. Another pyrimidine nucleoside, 1-β-D-arabinofurano-sylcytosine hydrochloride, was found to be at least as effective as IUDR in treating this infection. |
| doi_str_mv | 10.3181/00379727-111-27884 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_83122257</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.3181_00379727-111-27884</sage_id><sourcerecordid>83122257</sourcerecordid><originalsourceid>FETCH-LOGICAL-p249t-b6a6156a78ffd39ff6a56b532543bcc8032a8f50a5e96091ba1083ba5bd1fd713</originalsourceid><addsrcrecordid>eNo10L1OwzAUhmELgWgp3AADysRm6mPXTjxW5aeISgzAwmI5iV1cpXGwE0RuiwvhmmhpO53l0dGnF6FLIDcMMhgTwlKZ0hQDAKZplk2O0BA445gJKY_RcAvwVgzQWYwrQoCnVJyiATApORNiiN6nReu-XNsn3iaAf3_wLZ4Gnbva2y7o2se-KvrWR1ebZN6XwRcflQ-uNMl0qV0d22RuQmNi8uLWTWW-kycTdOtaF8_RidVVNBf7O0Jv93evszlePD88zqYL3NCJbHEutAAudJpZWzJprdBc5JxRPmF5UWSEUZ1ZTjQ3UhAJuQaSsVzzvARbpsBG6Hr3twn-szOxVWsXC1NVuja-iypjQCnl6QZe7WGXr02pmuDWOvTqUGMDxjsQ9dKole9CvRmugKhtb3XorTa91X9v9gfs2HFL</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>83122257</pqid></control><display><type>article</type><title>Activity of 1-β-D-Arabinofuranosylcytosine Hydrochloride Against Herpes Simplex Keratitis</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Underwood, Gerald E.</creator><creatorcontrib>Underwood, Gerald E.</creatorcontrib><description>Summary
The antiviral activity of 5-iodo-2′-deoxyuridine in treating herpes simplex keratitis in rabbits was confirmed. Another pyrimidine nucleoside, 1-β-D-arabinofurano-sylcytosine hydrochloride, was found to be at least as effective as IUDR in treating this infection.</description><identifier>ISSN: 0037-9727</identifier><identifier>EISSN: 1535-3699</identifier><identifier>DOI: 10.3181/00379727-111-27884</identifier><identifier>PMID: 13995366</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Antiviral Agents ; Cytarabine ; Humans ; Keratitis ; Keratitis, Dendritic ; Keratitis, Herpetic ; Nucleosides ; Old Medline</subject><ispartof>Proceedings of the Society for Experimental Biology and Medicine, 1962-12, Vol.111 (3), p.660-664</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/13995366$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Underwood, Gerald E.</creatorcontrib><title>Activity of 1-β-D-Arabinofuranosylcytosine Hydrochloride Against Herpes Simplex Keratitis</title><title>Proceedings of the Society for Experimental Biology and Medicine</title><addtitle>Proc Soc Exp Biol Med</addtitle><description>Summary
The antiviral activity of 5-iodo-2′-deoxyuridine in treating herpes simplex keratitis in rabbits was confirmed. Another pyrimidine nucleoside, 1-β-D-arabinofurano-sylcytosine hydrochloride, was found to be at least as effective as IUDR in treating this infection.</description><subject>Antiviral Agents</subject><subject>Cytarabine</subject><subject>Humans</subject><subject>Keratitis</subject><subject>Keratitis, Dendritic</subject><subject>Keratitis, Herpetic</subject><subject>Nucleosides</subject><subject>Old Medline</subject><issn>0037-9727</issn><issn>1535-3699</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1962</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo10L1OwzAUhmELgWgp3AADysRm6mPXTjxW5aeISgzAwmI5iV1cpXGwE0RuiwvhmmhpO53l0dGnF6FLIDcMMhgTwlKZ0hQDAKZplk2O0BA445gJKY_RcAvwVgzQWYwrQoCnVJyiATApORNiiN6nReu-XNsn3iaAf3_wLZ4Gnbva2y7o2se-KvrWR1ebZN6XwRcflQ-uNMl0qV0d22RuQmNi8uLWTWW-kycTdOtaF8_RidVVNBf7O0Jv93evszlePD88zqYL3NCJbHEutAAudJpZWzJprdBc5JxRPmF5UWSEUZ1ZTjQ3UhAJuQaSsVzzvARbpsBG6Hr3twn-szOxVWsXC1NVuja-iypjQCnl6QZe7WGXr02pmuDWOvTqUGMDxjsQ9dKole9CvRmugKhtb3XorTa91X9v9gfs2HFL</recordid><startdate>196212</startdate><enddate>196212</enddate><creator>Underwood, Gerald E.</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>196212</creationdate><title>Activity of 1-β-D-Arabinofuranosylcytosine Hydrochloride Against Herpes Simplex Keratitis</title><author>Underwood, Gerald E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p249t-b6a6156a78ffd39ff6a56b532543bcc8032a8f50a5e96091ba1083ba5bd1fd713</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1962</creationdate><topic>Antiviral Agents</topic><topic>Cytarabine</topic><topic>Humans</topic><topic>Keratitis</topic><topic>Keratitis, Dendritic</topic><topic>Keratitis, Herpetic</topic><topic>Nucleosides</topic><topic>Old Medline</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Underwood, Gerald E.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Proceedings of the Society for Experimental Biology and Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Underwood, Gerald E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Activity of 1-β-D-Arabinofuranosylcytosine Hydrochloride Against Herpes Simplex Keratitis</atitle><jtitle>Proceedings of the Society for Experimental Biology and Medicine</jtitle><addtitle>Proc Soc Exp Biol Med</addtitle><date>1962-12</date><risdate>1962</risdate><volume>111</volume><issue>3</issue><spage>660</spage><epage>664</epage><pages>660-664</pages><issn>0037-9727</issn><eissn>1535-3699</eissn><abstract>Summary
The antiviral activity of 5-iodo-2′-deoxyuridine in treating herpes simplex keratitis in rabbits was confirmed. Another pyrimidine nucleoside, 1-β-D-arabinofurano-sylcytosine hydrochloride, was found to be at least as effective as IUDR in treating this infection.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>13995366</pmid><doi>10.3181/00379727-111-27884</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0037-9727 |
| ispartof | Proceedings of the Society for Experimental Biology and Medicine, 1962-12, Vol.111 (3), p.660-664 |
| issn | 0037-9727 1535-3699 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_83122257 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Antiviral Agents Cytarabine Humans Keratitis Keratitis, Dendritic Keratitis, Herpetic Nucleosides Old Medline |
| title | Activity of 1-β-D-Arabinofuranosylcytosine Hydrochloride Against Herpes Simplex Keratitis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-27T23%3A13%3A43IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Activity%20of%201-%CE%B2-D-Arabinofuranosylcytosine%20Hydrochloride%20Against%20Herpes%20Simplex%20Keratitis&rft.jtitle=Proceedings%20of%20the%20Society%20for%20Experimental%20Biology%20and%20Medicine&rft.au=Underwood,%20Gerald%20E.&rft.date=1962-12&rft.volume=111&rft.issue=3&rft.spage=660&rft.epage=664&rft.pages=660-664&rft.issn=0037-9727&rft.eissn=1535-3699&rft_id=info:doi/10.3181/00379727-111-27884&rft_dat=%3Cproquest_pubme%3E83122257%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=83122257&rft_id=info:pmid/13995366&rft_sage_id=10.3181_00379727-111-27884&rfr_iscdi=true |