Activity of 1-β-D-Arabinofuranosylcytosine Hydrochloride Against Herpes Simplex Keratitis

Activity of 1-β-D-Arabinofuranosylcytosine Hydrochloride Against Herpes Simplex Keratitis

Summary The antiviral activity of 5-iodo-2′-deoxyuridine in treating herpes simplex keratitis in rabbits was confirmed. Another pyrimidine nucleoside, 1-β-D-arabinofurano-sylcytosine hydrochloride, was found to be at least as effective as IUDR in treating this infection.

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Bibliographische Detailangaben
Veröffentlicht in:Proceedings of the Society for Experimental Biology and Medicine 1962-12, Vol.111 (3), p.660-664
1. Verfasser: Underwood, Gerald E.
Format: Artikel
Sprache:eng
Schlagworte:
Antiviral Agents
Cytarabine
Humans
Keratitis
Keratitis, Dendritic
Keratitis, Herpetic
Nucleosides
Old Medline
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Zusammenfassung:Summary The antiviral activity of 5-iodo-2′-deoxyuridine in treating herpes simplex keratitis in rabbits was confirmed. Another pyrimidine nucleoside, 1-β-D-arabinofurano-sylcytosine hydrochloride, was found to be at least as effective as IUDR in treating this infection.
ISSN:0037-9727
1535-3699
DOI:10.3181/00379727-111-27884