Effects of Anti-Inflammatory Steroids on Mouse Embryonic Movements During Palatal Development

The frequency of spontaneous embryonic muscular movements was recorded for embryos from mice treated with cortisone or triamcinolone. Movement was significantly reduced in A/J strain mouse embryos exposed to these anti-inflammatory agents. Cleft palates induced by the drugs may originate from failur...

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Veröffentlicht in:	Journal of dental research 1975-11, Vol.54 (6), p.1200-1206
Hauptverfasser:	Walker, Bruce E., Quarles, Joan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - pharmacology Cortisone - pharmacology Dentistry Embryo, Mammalian - physiology Mice Mice, Inbred C57BL - embryology Mice, Inbred Strains - embryology Movement Palate - embryology Triamcinolone - pharmacology
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Zusammenfassung:	The frequency of spontaneous embryonic muscular movements was recorded for embryos from mice treated with cortisone or triamcinolone. Movement was significantly reduced in A/J strain mouse embryos exposed to these anti-inflammatory agents. Cleft palates induced by the drugs may originate from failure of the embryonic tongue to be withdrawn from between the palatine shelves.
ISSN:	0022-0345 1544-0591
DOI:	10.1177/00220345750540061701