Red cells preserved with 10% hydroxyethyl starch: Effect of prefreeze washing

Prefreeze washing of red cells with saline and other wash solutions before freezing with 10% hydroxyethyl starch does not yield an improved product after thawing. The saline stabilities and cell recoveries are reduced and the level of supernatant hemoglobin increased. These data further support the...

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Veröffentlicht in:Cryobiology 1975-10, Vol.12 (5), p.513-516
Hauptverfasser: Weatherbee, L., Allen, E.D., Spencer, H.H., Lindenauer, S.M., Permoad, P.A.
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container_end_page 516
container_issue 5
container_start_page 513
container_title Cryobiology
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creator Weatherbee, L.
Allen, E.D.
Spencer, H.H.
Lindenauer, S.M.
Permoad, P.A.
description Prefreeze washing of red cells with saline and other wash solutions before freezing with 10% hydroxyethyl starch does not yield an improved product after thawing. The saline stabilities and cell recoveries are reduced and the level of supernatant hemoglobin increased. These data further support the use of 14% as the most acceptable concentration of hydroxyethyl starch for cryopreservation of red cells.
doi_str_mv 10.1016/0011-2240(75)90033-4
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source MEDLINE; Elsevier ScienceDirect Journals
subjects Blood Preservation
Cryoprotective Agents
Erythrocytes - drug effects
Freezing
Humans
Hydroxyethyl Starch Derivatives - pharmacology
Starch - analogs & derivatives
title Red cells preserved with 10% hydroxyethyl starch: Effect of prefreeze washing
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