Red cells preserved with 10% hydroxyethyl starch: Effect of prefreeze washing

Prefreeze washing of red cells with saline and other wash solutions before freezing with 10% hydroxyethyl starch does not yield an improved product after thawing. The saline stabilities and cell recoveries are reduced and the level of supernatant hemoglobin increased. These data further support the...

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Veröffentlicht in:	Cryobiology 1975-10, Vol.12 (5), p.513-516
Hauptverfasser:	Weatherbee, L., Allen, E.D., Spencer, H.H., Lindenauer, S.M., Permoad, P.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood Preservation Cryoprotective Agents Erythrocytes - drug effects Freezing Humans Hydroxyethyl Starch Derivatives - pharmacology Starch - analogs & derivatives
Online-Zugang:	Volltext
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Zusammenfassung:	Prefreeze washing of red cells with saline and other wash solutions before freezing with 10% hydroxyethyl starch does not yield an improved product after thawing. The saline stabilities and cell recoveries are reduced and the level of supernatant hemoglobin increased. These data further support the use of 14% as the most acceptable concentration of hydroxyethyl starch for cryopreservation of red cells.
ISSN:	0011-2240 1090-2392
DOI:	10.1016/0011-2240(75)90033-4