Determination of vitamin A acid in human plasma after oral administration

Determination of vitamin A acid in human plasma after oral administration

A quantitative method is described for detecting vitamin A acid in human plasma after oral administration. Levels of vitamin A acid ranging between 112 and 329 μg./ 100 ml. were obtained, while vitamin A alcohol levels ranged between 33 and 63 μg./ 100 ml. Both antimony trichloride spectra and direc...

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Veröffentlicht in:Archives of biochemistry and biophysics 1962-08, Vol.98 (2), p.337-341
1. Verfasser: Jurkowitz, Lawrence
Format: Artikel
Sprache:eng
Schlagworte:
Administration, Oral
Humans
Old Medline
Tretinoin
Vitamin A - blood
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Zusammenfassung:A quantitative method is described for detecting vitamin A acid in human plasma after oral administration. Levels of vitamin A acid ranging between 112 and 329 μg./ 100 ml. were obtained, while vitamin A alcohol levels ranged between 33 and 63 μg./ 100 ml. Both antimony trichloride spectra and direct spectra obtained with this method are presented. Some of the difficulties in determining vitamin A acid quantitatively are discussed.
ISSN:0003-9861
1096-0384
DOI:10.1016/0003-9861(62)90192-3