Effect of fasting on fibrinolysis and blood coagulation

The effect of 60 hours' fasting on fibrinolytic activity, Stypven time and serum cholesterol was studied in 12 healthy men. The fibrinolysis time was 32.0 hours after a night's fasting, 19.7 hours after 36 hours' fasting and 14.4 hours after 60 hours' fasting. The change was statistically significant after 36 hours of fasting, and the fibrinolytic activity did not change significantly during the following fasting day. The Stypven coagulation time after a night's fasting was 19.3 seconds; after 36 hours' fasting, 20.6 seconds; and after 60 hours' fasting, 22.5 seconds. The change was statistically almost significant after 60 hours' fasting. After fasting for 36 hours the change was not statistically significant. The serum cholesterol increased significantly during 12 to 36 hours' fasting (from 259 to 281 mg.%) and increased significantly during the next 24 hours of fasting (to 296 mg.%).