The presence in the fungus Cordyceps militaris of nuclear proteins resembling histones

The typical mammalian histones are not present in the fungus Cordyceps militaris. However, two proteins are consistently found in acid extracts of the nuclear fraction. They are moderately lysine-rich, similar to the histones in molecular weight, but different from any known mammalian histone fracti...

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Veröffentlicht in:Archives of biochemistry and biophysics 1975-01, Vol.170 (1), p.315-325
Hauptverfasser: Indik, Zena K., Keller, Barbara J., Marks, Dawn B.
Format: Artikel
Sprache:eng
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Zusammenfassung:The typical mammalian histones are not present in the fungus Cordyceps militaris. However, two proteins are consistently found in acid extracts of the nuclear fraction. They are moderately lysine-rich, similar to the histones in molecular weight, but different from any known mammalian histone fraction in mobility on acidic polyacrylamide gels. These acid soluble nuclear proteins of C. militaris differ to some extent from the basic nuclear proteins found in yeasts and the filamentous fungus, Neurospora crassa. Unlike the arginine-rich histone fractions, the moderately lysine-rich histomes are found in both higher and unicellular eukaryotes. It is suggested that the moderately lysine-rich histones form the core which is essential for maintaining the unique subunit structure of chromatin.
ISSN:0003-9861
1096-0384
DOI:10.1016/0003-9861(75)90123-X