Crystals of Protein Nature in the Cytoplasm of Lymphatic Cells in a Case of Lymphoreticular Malignancy

Crystals of Protein Nature in the Cytoplasm of Lymphatic Cells in a Case of Lymphoreticular Malignancy

The occurrence of crystals in the cytoplasm of lymphatic cells in a case of lymphoreticular malignancy—probably lymphocytic leukemia—is reported. Histochemistry revealed the protein nature of these crystals. It appeared that the protein was water-soluble, with no admixture of polysaccharides. Electr...

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Veröffentlicht in:Blood 1962-10, Vol.20 (4), p.492-500
Hauptverfasser: de Man, J. C. H, Meiners, W B. H
Format: Artikel
Sprache:eng
Schlagworte:
Humans
Lymph Nodes - chemistry
Lymphatic Vessels
Lymphoma - chemistry
Neoplasms
Old Medline
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Zusammenfassung:The occurrence of crystals in the cytoplasm of lymphatic cells in a case of lymphoreticular malignancy—probably lymphocytic leukemia—is reported. Histochemistry revealed the protein nature of these crystals. It appeared that the protein was water-soluble, with no admixture of polysaccharides. Electron microscopy of the crystals showed a fine structure of regularly arranged thin lines with a spacing of 100 Å. The crystals were surrounded by membranes of the endoplasmic reticulum.
ISSN:0006-4971
1528-0020
DOI:10.1182/blood.V20.4.492.492