The effects of normal cerebrospinal fluid on blood clotting and fibroblast growth

The effects of normal cerebrospinal fluid on blood clotting and fibroblast growth

In 50 normal CSF samples, no thrombin, fibinogen, prothrombin, proconvertin, proaccelerin, antihemophilic globulin or thromboplastin activity was found. These samples had no effects different from those produced by artificial control solutions on the coagulation time of a thrombin-fibrinogen system,...

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Veröffentlicht in:The Journal of surgical research 1961-01, Vol.1 (4), p.260-266
Hauptverfasser: Wilkins, Robert H., Smith, Wirt, Anlyan, William G., Hetherington, Duncan C., Woodhall, Barnes
Format: Artikel
Sprache:eng
Schlagworte:
Blood Coagulation
Cerebrospinal Fluid - chemistry
Connective Tissue - physiology
Fibroblasts
Humans
Old Medline
Thrombosis
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Zusammenfassung:In 50 normal CSF samples, no thrombin, fibinogen, prothrombin, proconvertin, proaccelerin, antihemophilic globulin or thromboplastin activity was found. These samples had no effects different from those produced by artificial control solutions on the coagulation time of a thrombin-fibrinogen system, and they demonsrated no fibrinolytic activity. In addition, they had no effect on chick fibroblast growth. There is no idication from these results that CSF specifically interferes with the healing of ruptured intracranial aneurysms.
ISSN:0022-4804
1095-8673
DOI:10.1016/S0022-4804(61)80028-0