Anesthetic solubility coefficients for maternal and fetal blood
Solubility coefficients for seven inhalation anesthetic agnets were determined in maternal and fetal blood at 37 C. Halothane, isoflurane, diethyl ether, and nitrous oxide were significantly more soluble in maternal than in fetal blood, while methoxyflurane, fluroxene, and cyclopropane were signific...
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| Veröffentlicht in: | Anesthesiology (Philadelphia) 1975-07, Vol.43 (1), p.100-102 |
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| container_title | Anesthesiology (Philadelphia) |
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| creator | Gibbs, C P Munson, E S Tham, M K |
| description | Solubility coefficients for seven inhalation anesthetic agnets were determined in maternal and fetal blood at 37 C. Halothane, isoflurane, diethyl ether, and nitrous oxide were significantly more soluble in maternal than in fetal blood, while methoxyflurane, fluroxene, and cyclopropane were significantly less soluble. Reasons for these differences cannot be accounted for by differences in the type or amount of hemoglobin present. |
| doi_str_mv | 10.1097/00000542-197507000-00020 |
| format | Article |
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Halothane, isoflurane, diethyl ether, and nitrous oxide were significantly more soluble in maternal than in fetal blood, while methoxyflurane, fluroxene, and cyclopropane were significantly less soluble. Reasons for these differences cannot be accounted for by differences in the type or amount of hemoglobin present.</description><identifier>ISSN: 0003-3022</identifier><identifier>DOI: 10.1097/00000542-197507000-00020</identifier><identifier>PMID: 238431</identifier><language>eng</language><publisher>United States</publisher><subject>Anesthesia, Inhalation ; Anesthesia, Obstetrical ; Anesthetics ; Blood ; Cyclopropanes ; Erythrocytes ; Ethers ; Ethyl Ethers ; Female ; Fetal Blood ; Halothane ; Hematocrit ; Humans ; Isoflurane ; Maternal-Fetal Exchange ; Methoxyflurane ; Nitrous Oxide ; Plasma ; Pregnancy ; Solubility</subject><ispartof>Anesthesiology (Philadelphia), 1975-07, Vol.43 (1), p.100-102</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c359t-556a46d327973a37181942eb789fc50a9850cef2b9cc9adc738b7368132ce06d3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/238431$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gibbs, C P</creatorcontrib><creatorcontrib>Munson, E S</creatorcontrib><creatorcontrib>Tham, M K</creatorcontrib><title>Anesthetic solubility coefficients for maternal and fetal blood</title><title>Anesthesiology (Philadelphia)</title><addtitle>Anesthesiology</addtitle><description>Solubility coefficients for seven inhalation anesthetic agnets were determined in maternal and fetal blood at 37 C. Halothane, isoflurane, diethyl ether, and nitrous oxide were significantly more soluble in maternal than in fetal blood, while methoxyflurane, fluroxene, and cyclopropane were significantly less soluble. Reasons for these differences cannot be accounted for by differences in the type or amount of hemoglobin present.</description><subject>Anesthesia, Inhalation</subject><subject>Anesthesia, Obstetrical</subject><subject>Anesthetics</subject><subject>Blood</subject><subject>Cyclopropanes</subject><subject>Erythrocytes</subject><subject>Ethers</subject><subject>Ethyl Ethers</subject><subject>Female</subject><subject>Fetal Blood</subject><subject>Halothane</subject><subject>Hematocrit</subject><subject>Humans</subject><subject>Isoflurane</subject><subject>Maternal-Fetal Exchange</subject><subject>Methoxyflurane</subject><subject>Nitrous Oxide</subject><subject>Plasma</subject><subject>Pregnancy</subject><subject>Solubility</subject><issn>0003-3022</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1975</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kEtPAyEQxzn4qtVv4IGTt1UeS4GTaRqrJk286JmwLEQMu1RgD_32Uls7yWRmkvnP4wcAxOgBI8kf0d5YSxosOUO8Fk11gs7ArEbaUETIFbjO-buWnFFxCS4IFS3FM_C0HG0uX7Z4A3MMU-eDLztoonXOG2_HkqGLCQ662DTqAPXYQ2dLzboQY38Dzp0O2d4e4xx8rp8_Vq_N5v3lbbXcNIYyWRrGFrpd9JRwyammHAssW2I7LqQzDGkpGDLWkU4aI3VvOBUdpwuBKTEWVeEc3B_mblP8merJavDZ2BD0aOOUlSCSif1zcyAOjSbFnJN1apv8oNNOYaT2uNQ_LnXCpf5wVendccfUDbY_CQ-s6C8namaq</recordid><startdate>197507</startdate><enddate>197507</enddate><creator>Gibbs, C P</creator><creator>Munson, E S</creator><creator>Tham, M K</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197507</creationdate><title>Anesthetic solubility coefficients for maternal and fetal blood</title><author>Gibbs, C P ; Munson, E S ; Tham, M K</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c359t-556a46d327973a37181942eb789fc50a9850cef2b9cc9adc738b7368132ce06d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1975</creationdate><topic>Anesthesia, Inhalation</topic><topic>Anesthesia, Obstetrical</topic><topic>Anesthetics</topic><topic>Blood</topic><topic>Cyclopropanes</topic><topic>Erythrocytes</topic><topic>Ethers</topic><topic>Ethyl Ethers</topic><topic>Female</topic><topic>Fetal Blood</topic><topic>Halothane</topic><topic>Hematocrit</topic><topic>Humans</topic><topic>Isoflurane</topic><topic>Maternal-Fetal Exchange</topic><topic>Methoxyflurane</topic><topic>Nitrous Oxide</topic><topic>Plasma</topic><topic>Pregnancy</topic><topic>Solubility</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gibbs, C P</creatorcontrib><creatorcontrib>Munson, E S</creatorcontrib><creatorcontrib>Tham, M K</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Anesthesiology (Philadelphia)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gibbs, C P</au><au>Munson, E S</au><au>Tham, M K</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Anesthetic solubility coefficients for maternal and fetal blood</atitle><jtitle>Anesthesiology (Philadelphia)</jtitle><addtitle>Anesthesiology</addtitle><date>1975-07</date><risdate>1975</risdate><volume>43</volume><issue>1</issue><spage>100</spage><epage>102</epage><pages>100-102</pages><issn>0003-3022</issn><abstract>Solubility coefficients for seven inhalation anesthetic agnets were determined in maternal and fetal blood at 37 C. Halothane, isoflurane, diethyl ether, and nitrous oxide were significantly more soluble in maternal than in fetal blood, while methoxyflurane, fluroxene, and cyclopropane were significantly less soluble. Reasons for these differences cannot be accounted for by differences in the type or amount of hemoglobin present.</abstract><cop>United States</cop><pmid>238431</pmid><doi>10.1097/00000542-197507000-00020</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Anesthesiology (Philadelphia), 1975-07, Vol.43 (1), p.100-102 |
| issn | 0003-3022 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Journals@Ovid Complete |
| subjects | Anesthesia, Inhalation Anesthesia, Obstetrical Anesthetics Blood Cyclopropanes Erythrocytes Ethers Ethyl Ethers Female Fetal Blood Halothane Hematocrit Humans Isoflurane Maternal-Fetal Exchange Methoxyflurane Nitrous Oxide Plasma Pregnancy Solubility |
| title | Anesthetic solubility coefficients for maternal and fetal blood |
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