Anesthetic solubility coefficients for maternal and fetal blood

Anesthetic solubility coefficients for maternal and fetal blood

Solubility coefficients for seven inhalation anesthetic agnets were determined in maternal and fetal blood at 37 C. Halothane, isoflurane, diethyl ether, and nitrous oxide were significantly more soluble in maternal than in fetal blood, while methoxyflurane, fluroxene, and cyclopropane were signific...

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Veröffentlicht in:Anesthesiology (Philadelphia) 1975-07, Vol.43 (1), p.100-102
Hauptverfasser: Gibbs, C P, Munson, E S, Tham, M K
Format: Artikel
Sprache:eng
Schlagworte:
Anesthesia, Inhalation
Anesthesia, Obstetrical
Anesthetics
Blood
Cyclopropanes
Erythrocytes
Ethers
Ethyl Ethers
Female
Fetal Blood
Halothane
Hematocrit
Humans
Isoflurane
Maternal-Fetal Exchange
Methoxyflurane
Nitrous Oxide
Plasma
Pregnancy
Solubility
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Zusammenfassung:Solubility coefficients for seven inhalation anesthetic agnets were determined in maternal and fetal blood at 37 C. Halothane, isoflurane, diethyl ether, and nitrous oxide were significantly more soluble in maternal than in fetal blood, while methoxyflurane, fluroxene, and cyclopropane were significantly less soluble. Reasons for these differences cannot be accounted for by differences in the type or amount of hemoglobin present.
ISSN:0003-3022
DOI:10.1097/00000542-197507000-00020