Structure Determination of the Anorexic Agent Mazindol

The anorexic agent mazindol was shown to exist as the carbinolamine tautomer 5-p-chlorophenyl-2,3-dihydro-5H-imidazo[2,1-a]isoindol-5-ol in solution and in the solid state. The later was established by diffuse UV reflectance spectroscopy.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of pharmaceutical sciences 1975-05, Vol.64 (5), p.829-831
Hauptverfasser:	Barcza, Sandor, Houlihan, William J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Carbon Isotopes Chemical Phenomena Chemistry diffuse reflectane-structure determination diffuse UV reflectance spectroscopy Indoles - analysis Isomerism Maazindol-structure determination Maazindol—structure determination, diffuse UV reflectance spectroscopy Magnetic Resonance Spectroscopy mazindol Mazindol - analysis Molecular Conformation Spectrophotometry, Infrared Spectrophotometry, Ultraviolet Structure determination-mazindol in solution and solid state Structure determination—mazindol in solution and solid state, diffuse UV reflectance spectroscopy UV spectroscopy UV spectroscopy, diffuse reflectane—structure determination, mazindol
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Beschreibung
Zusammenfassung:	The anorexic agent mazindol was shown to exist as the carbinolamine tautomer 5-p-chlorophenyl-2,3-dihydro-5H-imidazo[2,1-a]isoindol-5-ol in solution and in the solid state. The later was established by diffuse UV reflectance spectroscopy.
ISSN:	0022-3549 1520-6017
DOI:	10.1002/jps.2600640522