Selective growth of malignant cells by in vitro incubation on Teflon

Selective growth of malignant cells by in vitro incubation on Teflon

The selective growth of malignant cells on non-adhesive Teflon substrates is reported. Neoplastically transformed cell lines of human and murine origin proliferated on Teflon whereas similarly seeded normal non-tumorigenic cells were unable to undergo cell division and subsequent growth. This substr...

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Veröffentlicht in:Experimental cell research 1975-07, Vol.93 (2), p.508-512
Hauptverfasser: Paranjpe, M.S., Boone, Ch.W., del Ande Eaton, S.
Format: Artikel
Sprache:eng
Schlagworte:
Cell Adhesion
Cell Division
Cell Line
Cell Survival
Cell Transformation, Neoplastic
Mitosis
Plastics
Polytetrafluoroethylene
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Zusammenfassung:The selective growth of malignant cells on non-adhesive Teflon substrates is reported. Neoplastically transformed cell lines of human and murine origin proliferated on Teflon whereas similarly seeded normal non-tumorigenic cells were unable to undergo cell division and subsequent growth. This substrate should be especially useful in establishing primary cultures from human tumor material.
ISSN:0014-4827
1090-2422
DOI:10.1016/0014-4827(75)90484-X