Erythropoietic Activity of Tissue Homogenates.
Summary Homogenates of rat liver, kidney, brain, spleen and muscle prepared in modified Tyrode's solution and injected into the rat are capable of stimulating erythropoiesis as measured by Fe59 incorporation into red cells and reticulocyte counts. The activity of the homogenates does not appear...
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Veröffentlicht in: | Experimental biology and medicine (Maywood, N.J.) N.J.), 1961-12, Vol.108 (3), p.793-796 |
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container_title | Experimental biology and medicine (Maywood, N.J.) |
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creator | Rambach, W. A. Alt, H. L. Cooper, J. A. D. |
description | Summary
Homogenates of rat liver, kidney, brain, spleen and muscle prepared in modified Tyrode's solution and injected into the rat are capable of stimulating erythropoiesis as measured by Fe59 incorporation into red cells and reticulocyte counts. The activity of the homogenates does not appear to be a nonspecific effect. Certain points of similarity are noted between the homogenates and plasma erythropoietin. |
doi_str_mv | 10.3181/00379727-108-27070 |
format | Article |
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Homogenates of rat liver, kidney, brain, spleen and muscle prepared in modified Tyrode's solution and injected into the rat are capable of stimulating erythropoiesis as measured by Fe59 incorporation into red cells and reticulocyte counts. The activity of the homogenates does not appear to be a nonspecific effect. Certain points of similarity are noted between the homogenates and plasma erythropoietin.</description><identifier>ISSN: 0037-9727</identifier><identifier>ISSN: 1535-3702</identifier><identifier>EISSN: 1535-3699</identifier><identifier>DOI: 10.3181/00379727-108-27070</identifier><identifier>PMID: 14490089</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Hematopoiesis - pharmacology ; Old Medline ; Tissue Extracts - pharmacology</subject><ispartof>Experimental biology and medicine (Maywood, N.J.), 1961-12, Vol.108 (3), p.793-796</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c341t-18025af994c9a9e2c1f14ac2fcab62a2b90e840f2ccda546a0ef6212c49aab9b3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14490089$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rambach, W. A.</creatorcontrib><creatorcontrib>Alt, H. L.</creatorcontrib><creatorcontrib>Cooper, J. A. D.</creatorcontrib><title>Erythropoietic Activity of Tissue Homogenates.</title><title>Experimental biology and medicine (Maywood, N.J.)</title><addtitle>Proc Soc Exp Biol Med</addtitle><description>Summary
Homogenates of rat liver, kidney, brain, spleen and muscle prepared in modified Tyrode's solution and injected into the rat are capable of stimulating erythropoiesis as measured by Fe59 incorporation into red cells and reticulocyte counts. The activity of the homogenates does not appear to be a nonspecific effect. Certain points of similarity are noted between the homogenates and plasma erythropoietin.</description><subject>Hematopoiesis - pharmacology</subject><subject>Old Medline</subject><subject>Tissue Extracts - pharmacology</subject><issn>0037-9727</issn><issn>1535-3702</issn><issn>1535-3699</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1961</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kDFPwzAQhS0EoqXwBxhQJra0dxcnsceqAopUiaXMluPaJVVTFztB6r8npUVsTCc9fe9J9zF2jzDOUOAEICtlSWWKIFIqoYQLNsQ8y9OskPKSDY9AeiQG7CbGDQDmJRXXbICcSwAhh2z8FA7tR_B7X9u2NsnUtPVX3R4S75JlHWNnk7lv_NrudGvj-JZdOb2N9u58R-z9-Wk5m6eLt5fX2XSRmoxjm6IAyrWTkhuppSWDDrk25IyuCtJUSbCCgyNjVjrnhQbrCkIyXGpdySobscfT7j74z87GVjV1NHa71Tvru6gESUTKqQfpBJrgYwzWqX2oGx0OCkEdLalfS30g1I-lvvRwXu-qxq7-KmctPTA5AVGvrdr4Luz6b_-b_Aazo2-7</recordid><startdate>196112</startdate><enddate>196112</enddate><creator>Rambach, W. A.</creator><creator>Alt, H. L.</creator><creator>Cooper, J. A. D.</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>196112</creationdate><title>Erythropoietic Activity of Tissue Homogenates.</title><author>Rambach, W. A. ; Alt, H. L. ; Cooper, J. A. D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c341t-18025af994c9a9e2c1f14ac2fcab62a2b90e840f2ccda546a0ef6212c49aab9b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1961</creationdate><topic>Hematopoiesis - pharmacology</topic><topic>Old Medline</topic><topic>Tissue Extracts - pharmacology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rambach, W. A.</creatorcontrib><creatorcontrib>Alt, H. L.</creatorcontrib><creatorcontrib>Cooper, J. A. D.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rambach, W. A.</au><au>Alt, H. L.</au><au>Cooper, J. A. D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Erythropoietic Activity of Tissue Homogenates.</atitle><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle><addtitle>Proc Soc Exp Biol Med</addtitle><date>1961-12</date><risdate>1961</risdate><volume>108</volume><issue>3</issue><spage>793</spage><epage>796</epage><pages>793-796</pages><issn>0037-9727</issn><issn>1535-3702</issn><eissn>1535-3699</eissn><abstract>Summary
Homogenates of rat liver, kidney, brain, spleen and muscle prepared in modified Tyrode's solution and injected into the rat are capable of stimulating erythropoiesis as measured by Fe59 incorporation into red cells and reticulocyte counts. The activity of the homogenates does not appear to be a nonspecific effect. Certain points of similarity are noted between the homogenates and plasma erythropoietin.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>14490089</pmid><doi>10.3181/00379727-108-27070</doi><tpages>4</tpages></addata></record> |
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source | MEDLINE; Alma/SFX Local Collection |
subjects | Hematopoiesis - pharmacology Old Medline Tissue Extracts - pharmacology |
title | Erythropoietic Activity of Tissue Homogenates. |
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