Erythropoietic Activity of Tissue Homogenates.

Erythropoietic Activity of Tissue Homogenates.

Summary Homogenates of rat liver, kidney, brain, spleen and muscle prepared in modified Tyrode's solution and injected into the rat are capable of stimulating erythropoiesis as measured by Fe59 incorporation into red cells and reticulocyte counts. The activity of the homogenates does not appear...

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Veröffentlicht in:Experimental biology and medicine (Maywood, N.J.) N.J.), 1961-12, Vol.108 (3), p.793-796
Hauptverfasser: Rambach, W. A., Alt, H. L., Cooper, J. A. D.
Format: Artikel
Sprache:eng
Schlagworte:
Hematopoiesis - pharmacology
Old Medline
Tissue Extracts - pharmacology
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Zusammenfassung:Summary Homogenates of rat liver, kidney, brain, spleen and muscle prepared in modified Tyrode's solution and injected into the rat are capable of stimulating erythropoiesis as measured by Fe59 incorporation into red cells and reticulocyte counts. The activity of the homogenates does not appear to be a nonspecific effect. Certain points of similarity are noted between the homogenates and plasma erythropoietin.
ISSN:0037-9727
1535-3702
1535-3699
DOI:10.3181/00379727-108-27070