A physicochemical study of an antifungal antibiotic from Bacillus subtilis

A physicochemical study of an antifungal antibiotic from Bacillus subtilis

An antifungal antibiotic from the culture filtrates of a Bacillus subtilis strain has been purified by extraction procedures and by calcium phosphate chromatography. Both in the ultracentrifuge and electrophoresis, the purified antibiotic revealed a single peak. Data have been presented concerning t...

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Veröffentlicht in:Archives of biochemistry and biophysics 1961-11, Vol.95 (2), p.251-255
Hauptverfasser: Van Vuuren, P.J., Joubert, F.J., Serfontein, W.J.
Format: Artikel
Sprache:eng
Schlagworte:
Antifungal Agents - chemistry
Bacillus subtilis
Old Medline
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Zusammenfassung:An antifungal antibiotic from the culture filtrates of a Bacillus subtilis strain has been purified by extraction procedures and by calcium phosphate chromatography. Both in the ultracentrifuge and electrophoresis, the purified antibiotic revealed a single peak. Data have been presented concerning the sedimentation, diffusion, partial specific volume, and the electrophoretic mobility of the antibiotic. A molecular weight of 54,100 and a frictional ratio of 1.26 were calculated for the antibiotic.
ISSN:0003-9861
1096-0384
DOI:10.1016/0003-9861(61)90142-4