Factor suppressing α-foetoprotein production in newborn mice

α-FoETOPROTEiN (AFP) is one of the main proteins of embryonic serum. Its synthesis begins in the yolk sac continues in embryonic liver and terminates in mice and rats at the beginning of the postnatal period 1,2 . Presumably a powerful suppression factor acts on AFP production by embryonic liver cel...

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Veröffentlicht in:Nature (London) 1975-05, Vol.255 (5505), p.244-245
Hauptverfasser: TUMYAN, BELLA G., SVET-MOLDAVSKY, GEORGE G., KARMANOVA, NATALIA V.
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Sprache:eng
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Zusammenfassung:α-FoETOPROTEiN (AFP) is one of the main proteins of embryonic serum. Its synthesis begins in the yolk sac continues in embryonic liver and terminates in mice and rats at the beginning of the postnatal period 1,2 . Presumably a powerful suppression factor acts on AFP production by embryonic liver cells after the embryonic period has finished. The present study was undertaken to determine this factor(s).
ISSN:0028-0836
1476-4687
DOI:10.1038/255244a0