Radiation Effects on Skin and Subcutaneous Tissue: A Quantitative Study of Collagen Content: Modification with l-Triiodothyronine

Radiation Effects on Skin and Subcutaneous Tissue: A Quantitative Study of Collagen Content: Modification with l-Triiodothyronine

The results of direct measurement indicate that hydroxyproline increases in irradiated skin and subcutaneous tissue. Under the influence of the thyroid analog L-triiodothyronine, this accumulation is reversed. The nonirradiated tissues which normally increased in hydroxyproline content with age have...

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Veröffentlicht in:Radiation Research 1961-12, Vol.15 (6), p.761-766
Hauptverfasser: Kitagawa, Toshio, Glicksman, Arvin S., Tyree, Ella B., Nickson, James J.
Format: Artikel
Sprache:eng
Schlagworte:
AGE
AMINO ACIDS
Biochemistry
BIOLOGY AND MEDICINE
COLLAGEN
Collagen - chemistry
Collagens
HORMONES
Humans
Ionizing radiation
Irradiation
Old Medline
ORGANIC IODINE COMPOUNDS
Physical trauma
Potable water
PROLINE
PROTEINS
Radiation dosage
RADIATION EFFECTS
SKIN
Skin - radiation effects
Subcutaneous Tissue
THYRONINE
Thyronines
TISSUES
Triiodothyronine - pharmacology
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Zusammenfassung:The results of direct measurement indicate that hydroxyproline increases in irradiated skin and subcutaneous tissue. Under the influence of the thyroid analog L-triiodothyronine, this accumulation is reversed. The nonirradiated tissues which normally increased in hydroxyproline content with age have also been found to have a decrease in this constituent. (auth)
ISSN:0033-7587
1938-5404
DOI:10.2307/3571112