Response to hypercapnia under ketamine anaesthesia
The respiratory response to hypercapnia in dogs anaesthetized with ketamine was increased. This respiratory stimulation was most probably due to a direct effect of the drug on the medullary respiratory neurones. This effect was not modified by preanaesthetic medication pentobarbitone 5 mg/kg or morp...
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| Veröffentlicht in: | Canadian Anaesthetists' Society journal 1975-07, Vol.22 (4), p.486-494 |
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| container_end_page | 494 |
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| container_title | Canadian Anaesthetists' Society journal |
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| creator | Soliman, M G Brindle, G F Kuster, G |
| description | The respiratory response to hypercapnia in dogs anaesthetized with ketamine was increased. This respiratory stimulation was most probably due to a direct effect of the drug on the medullary respiratory neurones. This effect was not modified by preanaesthetic medication pentobarbitone 5 mg/kg or morphine 0.1 mg/kg. Catecholamine response to hypercapnia was essentially the same as that reported by hypercapnic dogs anaesthetized with thiopentone. |
| doi_str_mv | 10.1007/BF03004864 |
| format | Article |
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This respiratory stimulation was most probably due to a direct effect of the drug on the medullary respiratory neurones. This effect was not modified by preanaesthetic medication pentobarbitone 5 mg/kg or morphine 0.1 mg/kg. Catecholamine response to hypercapnia was essentially the same as that reported by hypercapnic dogs anaesthetized with thiopentone.</description><subject>Acid-Base Equilibrium</subject><subject>Anesthesia, Intravenous</subject><subject>Animals</subject><subject>Atropine</subject><subject>Blood Pressure - drug effects</subject><subject>Carbon Dioxide - blood</subject><subject>Catecholamines - blood</subject><subject>Central Venous Pressure - drug effects</subject><subject>Dogs</subject><subject>Hypercapnia - physiopathology</subject><subject>Ketamine - antagonists & inhibitors</subject><subject>Ketamine - pharmacology</subject><subject>Morphine</subject><subject>Oxygen - blood</subject><subject>Pentobarbital</subject><subject>Preanesthetic Medication</subject><subject>Respiration - drug effects</subject><subject>Space life sciences</subject><issn>0008-2856</issn><issn>1496-8975</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1975</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkEtLw0AUhQdRaqxu3AtZuRCid56ZWWqxKhQE0XWYztzQaF7OJIv--6a00NXZfJxz-Ai5pfBIAfKnlyVwAKGVOCMJFUZl2uTynCQAoDOmpbokVzH-AnCeCzkjM0q54dokhH1h7Ls2Yjp06WbbY3C2byubjq3HkP7hYJuqxdS2FuOwwVjZa3JR2jrizTHn5Gf5-r14z1afbx-L51XmONVDpsyaMiXQMFyXwpVWWGmY40L6nLuSs-kJGG-lNuAs9-ClU7g_KxlHr_ic3B96-9D9j9N60VTRYV3bFrsxFprpnIGgE_hwAF3oYgxYFn2oGhu2BYViL6g4CZrgu2PruG7Qn9CDEb4D85ZfAA</recordid><startdate>197507</startdate><enddate>197507</enddate><creator>Soliman, M G</creator><creator>Brindle, G F</creator><creator>Kuster, G</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197507</creationdate><title>Response to hypercapnia under ketamine anaesthesia</title><author>Soliman, M G ; Brindle, G F ; Kuster, G</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c318t-69b1264e92ebf4cfa4a592c345d73cf3274509da5890ca3d0d5c6e2856523ed63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1975</creationdate><topic>Acid-Base Equilibrium</topic><topic>Anesthesia, Intravenous</topic><topic>Animals</topic><topic>Atropine</topic><topic>Blood Pressure - drug effects</topic><topic>Carbon Dioxide - blood</topic><topic>Catecholamines - blood</topic><topic>Central Venous Pressure - drug effects</topic><topic>Dogs</topic><topic>Hypercapnia - physiopathology</topic><topic>Ketamine - antagonists & inhibitors</topic><topic>Ketamine - pharmacology</topic><topic>Morphine</topic><topic>Oxygen - blood</topic><topic>Pentobarbital</topic><topic>Preanesthetic Medication</topic><topic>Respiration - drug effects</topic><topic>Space life sciences</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Soliman, M G</creatorcontrib><creatorcontrib>Brindle, G F</creatorcontrib><creatorcontrib>Kuster, G</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Canadian Anaesthetists' Society journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Soliman, M G</au><au>Brindle, G F</au><au>Kuster, G</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Response to hypercapnia under ketamine anaesthesia</atitle><jtitle>Canadian Anaesthetists' Society journal</jtitle><addtitle>Can Anaesth Soc J</addtitle><date>1975-07</date><risdate>1975</risdate><volume>22</volume><issue>4</issue><spage>486</spage><epage>494</epage><pages>486-494</pages><issn>0008-2856</issn><eissn>1496-8975</eissn><abstract>The respiratory response to hypercapnia in dogs anaesthetized with ketamine was increased. 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| fulltext | fulltext |
| identifier | ISSN: 0008-2856 |
| ispartof | Canadian Anaesthetists' Society journal, 1975-07, Vol.22 (4), p.486-494 |
| issn | 0008-2856 1496-8975 |
| language | eng |
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| source | MEDLINE; Springer Nature - Complete Springer Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Acid-Base Equilibrium Anesthesia, Intravenous Animals Atropine Blood Pressure - drug effects Carbon Dioxide - blood Catecholamines - blood Central Venous Pressure - drug effects Dogs Hypercapnia - physiopathology Ketamine - antagonists & inhibitors Ketamine - pharmacology Morphine Oxygen - blood Pentobarbital Preanesthetic Medication Respiration - drug effects Space life sciences |
| title | Response to hypercapnia under ketamine anaesthesia |
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