Determination of Sorbitol and Mannitol in Pharmaceuticals by GLC of Tris‐n‐Butyldiboronate Esters

A rapid method for determining sorbitol or mannitol in pharmaceuticals by GLC using the tris‐n‐butyldiboronate esters is described. An internal standard unrelated to the hexitols is utilized to avoid the problems of cross‐contamination introduced by the use of other hexitols.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of pharmaceutical sciences 1975-01, Vol.64 (1), p.128-129
1. Verfasser:	Sondack, David L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Boric Acids Boron Compounds butyldiboronate esters Chromatography, Gas - methods GLC-determination GLC—determination, sorbitol and mannitol in pharmaceuticals using tris‐n‐, butyldiboronate esters Mannitol - analysis Mannitol-GLC determination in pharmaceuticals using tris-n Mannitol—GLC determination in pharmaceuticals using tris‐n‐, butyldiboronate esters Sorbitol - analysis sorbitol and mannitol in pharmaceuticals using tris-n Sorbitol-GLC determination in pharmaceuticals using tris-n Sorbitol—GLC determination in pharmaceuticals using tris‐n‐,butyldiboronate esters
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Beschreibung
Zusammenfassung:	A rapid method for determining sorbitol or mannitol in pharmaceuticals by GLC using the tris‐n‐butyldiboronate esters is described. An internal standard unrelated to the hexitols is utilized to avoid the problems of cross‐contamination introduced by the use of other hexitols.
ISSN:	0022-3549 1520-6017
DOI:	10.1002/jps.2600640129