Type C Virus Production by a Continuous Line of Pig Oviduct Cells (PFT)

Animal Pathology Division, Health of Animals Branch, Agriculture Canada, Animal Diseases Research Institute (E), P.O. Box 11300, Postal Station ‘H’, Ottawa, Ontario, Canada. K2H 8P9 M. M. Lieber and G. J. Todaro Viral Leukemia and Lymphoma Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20014, U.S.A. Late passages of the PFT porcine oviduct cell line spontaneously release a typical type C virus antigenically related to the type C virus released from the PK(15) porcine kidney cell line. The PFT virus was non-infective for a large variety of cell lines. Type C virus can also be induced by BrdU treatment from earlier passages of the PFT cell line. Received 29 November 1974; accepted 7 January 1975.