The visualization of receptors for the Fc portion of the IgG molecule on human neutrophil leukocytes
Human neutrophils treated with either Fc or with intact IgG and subsequently with fluorescein-labelled anti-IgG showed binding of the Fc or the IgG to the cell membrane. Neutrophils did not appear to bind F(ab′) 2 fragments. Under suitable conditions, polar capping of fluorescence was seen. The data...
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| Veröffentlicht in: | Life sciences (1973) 1974-06, Vol.14 (12), p.2427-2430 |
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| container_end_page | 2430 |
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| container_issue | 12 |
| container_start_page | 2427 |
| container_title | Life sciences (1973) |
| container_volume | 14 |
| creator | Sajnani, Ashok N. Ranadive, Narendranath S. Movat, Henry Z. |
| description | Human neutrophils treated with either Fc or with intact IgG and subsequently with fluorescein-labelled anti-IgG showed binding of the Fc or the IgG to the cell membrane. Neutrophils did not appear to bind F(ab′)
2 fragments. Under suitable conditions, polar capping of fluorescence was seen. The data suggest receptors for Fc on the neutrophil membrane and mobility of these receptors. |
| doi_str_mv | 10.1016/0024-3205(74)90138-6 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0024-3205 |
| ispartof | Life sciences (1973), 1974-06, Vol.14 (12), p.2427-2430 |
| issn | 0024-3205 1879-0631 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_82814137 |
| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Fluorescent Antibody Technique Glucuronidase - metabolism Humans Immunoglobulin G - metabolism Neutrophils - immunology Receptor Aggregation Receptors, Fc - metabolism |
| title | The visualization of receptors for the Fc portion of the IgG molecule on human neutrophil leukocytes |
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