Radioprotection by Mitotic Inhibitors and Mercaptoethylamine
In the mouse, chemical interference with cellular proliferation alters the radiosensitivity of the bone marrow, and this results in protection from otherwise lethal x-irradiation. When intestinal damage is minimized by appropriate timing and dosage, many mitotic inhibitors increase radioresistance a...
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| Veröffentlicht in: | Science (American Association for the Advancement of Science) 1961-03, Vol.133 (3456), p.888-888 |
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| container_issue | 3456 |
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| container_title | Science (American Association for the Advancement of Science) |
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| creator | Rothe, William E. Grenan, Marie M. |
| description | In the mouse, chemical interference with cellular proliferation alters the radiosensitivity of the bone marrow, and this results in protection from otherwise lethal x-irradiation. When intestinal damage is minimized by appropriate timing and dosage, many mitotic inhibitors increase radioresistance and enhance the protective effects of mercaptoethylamine. |
| doi_str_mv | 10.1126/science.133.3456.888 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0036-8075 |
| ispartof | Science (American Association for the Advancement of Science), 1961-03, Vol.133 (3456), p.888-888 |
| issn | 0036-8075 1095-9203 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_82808755 |
| source | MEDLINE; JSTOR Archive Collection A-Z Listing; American Association for the Advancement of Science |
| subjects | AMINES Animals BIOLOGY AND MEDICINE BONE MARROW Cell Division - pharmacology CHEMICALS Cysteamine Dosage INTESTINE LETHAL DOSE Mercaptoethylamines - pharmacology MICE MITOSIS Old Medline Radiation dosage RADIATION PROTECTION Radiation tolerance RADIOSENSITIVITY X RADIATION X-Rays |
| title | Radioprotection by Mitotic Inhibitors and Mercaptoethylamine |
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