Congenital granular-cell myoblastoma

The clinical and pathologic features of congenital granular-cell myoblastoma in five infant girls are reported. One lesion, treated expectantly, progressively decreased in size and after 3 yr and 9 mo could not be detected, while two lesions which were incompletely excised did not recur. It is suggested that congenital granular-cell myoblastoma is caused by an intrauterine stimulus, and that this stimulus may possibly be production of estrogen by the fetus. Congenital granular-cell myoblastoma should be treated expectantly or by limited excision, and has an excellent prognosis.