Anaplastic giant‐cell carcinoma of the thyroid. A study of treatment and prognosis

In 79 cases of histologically verified anaplastic giant‐cell carcinoma, symptoms, treatment, and prognosis were documented. Seventy‐eight patients are dead, the mean survival time being 2.5 months. One patient is cured. It was concluded that surgery and/or radiotherapy alone are not sufficient. The...

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Veröffentlicht in:	Cancer 1975-05, Vol.35 (5), p.1293-1295
Hauptverfasser:	Jereb, B., Stjernswärd, J., Löwhagen, T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Female Giant Cell Tumors - drug therapy Giant Cell Tumors - radiotherapy Giant Cell Tumors - surgery Giant Cell Tumors - therapy Humans Male Methotrexate - therapeutic use Middle Aged Prognosis Thyroid Neoplasms - drug therapy Thyroid Neoplasms - radiotherapy Thyroid Neoplasms - surgery Thyroid Neoplasms - therapy Time Factors
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Zusammenfassung:	In 79 cases of histologically verified anaplastic giant‐cell carcinoma, symptoms, treatment, and prognosis were documented. Seventy‐eight patients are dead, the mean survival time being 2.5 months. One patient is cured. It was concluded that surgery and/or radiotherapy alone are not sufficient. The results from an additional 8 patients also treated with methotexate indicate a positive therapeutic effect, the mean survival time being 9.4 months. Disappearance of recurrent tumor or pulmonary metastases was noted in 2 patients.
ISSN:	0008-543X 1097-0142
DOI:	10.1002/1097-0142(197505)35:5<1293::AID-CNCR2820350504>3.0.CO;2-W