The management of resistant fluid-retention states with intravenous L-arginine monohydrochloride in combination with mercurial diuretics

The management of resistant fluid-retention states with intravenous L-arginine monohydrochloride in combination with mercurial diuretics

The daily intravenous administration of a large dose of l-arginine monohydrochloride is a safe and effective method of producing hyperchloremic acidosis and restoring responsiveness to mercurial diuretics in patients with refractory retention of fluid due to hepatic cirrhosis or congestive heart fai...

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Veröffentlicht in:The American heart journal 1961, Vol.61 (1), p.16-20
Hauptverfasser: Ogden, David A., Scherr, Lawrence, Spritz, Norton, Rubin, Albert L., Luckey, E.Hugh
Format: Artikel
Sprache:eng
Schlagworte:
Arginine - therapy
Disease Management
Diuretics - therapy
Edema - therapy
Heart Failure
Humans
Old Medline
Organomercury Compounds - therapy
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Zusammenfassung:The daily intravenous administration of a large dose of l-arginine monohydrochloride is a safe and effective method of producing hyperchloremic acidosis and restoring responsiveness to mercurial diuretics in patients with refractory retention of fluid due to hepatic cirrhosis or congestive heart failure. Results obtained with 5 patients thus treated, and the advantages of this agent in certain clinical situations, are discussed.
ISSN:0002-8703
1097-6744
DOI:10.1016/0002-8703(61)90511-7