Fibrinolytic Activities present in Human Blood Platelets

BLOOD platelets have been shown to contain antiplasmin activity 1–3 . The experiments to be described in this communication demonstrate that blood platelets interfere in still another way in fibrinolysis. The fibrinolytic activity brought about by streptokinase comprises two steps 4 : (1) activation...

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Veröffentlicht in:Nature (London) 1961-01, Vol.189 (4760), p.238-239
Hauptverfasser: HOLEMANS, RUDOLF, GROSS, RUDOLF
Format: Artikel
Sprache:eng
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Zusammenfassung:BLOOD platelets have been shown to contain antiplasmin activity 1–3 . The experiments to be described in this communication demonstrate that blood platelets interfere in still another way in fibrinolysis. The fibrinolytic activity brought about by streptokinase comprises two steps 4 : (1) activation of a proactivator which could be identical in man with plasminogen ; (2) transformation of plasminogen to plasmin by the activator, resulting from reaction (1).
ISSN:0028-0836
1476-4687
DOI:10.1038/189238a0