Electrophoretic Mobility of Cultured Mesodermal Tissue Cells

AMBROSE et al. 1 have shown that individual tumour cells from hamster kidney possess a significantly greater electrophoretic mobility than normal homologous kidney cells. Later, Purdom et al. 2 obtained a correlation between the development of a mouse sarcoma and the progressive increase in the negative electrophoretic mobility of individual cells obtained from this sarcoma at various stages of its development. As the tumour cell acquired more malignant properties, evinced by the formation of early metastases, the negative electrophoretic mobility of individual cells was observed to have increased.