Effect of the thyroid on butyrate oxidation in the rat heart

Effect of the thyroid on butyrate oxidation in the rat heart

Oxidation of butyrate by rat heart homogenates in the presence of malate, nicotinamide or endogenous “sparkers” has been studied. It was found that heart homogenates from hyperthyroid rats oxidized butyrate at a higher rate than those from normal or hypothyroid animals. It is suggested that these fi...

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Veröffentlicht in:Biochemical pharmacology 1960-05, Vol.3 (2), p.85-88
Hauptverfasser: Deitrich, R.A., Smith, D.L.
Format: Artikel
Sprache:eng
Schlagworte:
Butyrates - metabolism
Lipid Metabolism
Myocardium - metabolism
Old Medline
Oxidation-Reduction
Thyroid Gland - physiology
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Zusammenfassung:Oxidation of butyrate by rat heart homogenates in the presence of malate, nicotinamide or endogenous “sparkers” has been studied. It was found that heart homogenates from hyperthyroid rats oxidized butyrate at a higher rate than those from normal or hypothyroid animals. It is suggested that these findings may have some bearings on the mechanisms of cardiac abnormalities associated with thyroid dysfunction.
ISSN:0006-2952
1873-2968
DOI:10.1016/0006-2952(60)90024-1