The estimation of thyroxine in human plasma by an electrophoretic technique

A new method for the determination of thyroxine in blood is described. It relies upon the quantitative dependence of the distribution of thyroxine between albumin and thyroxine-binding protein when exogenous 131I-labelled thyroxine is added to serum in vitro. Preliminary results suggest an accuracy...

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Veröffentlicht in:Clinica chimica acta 1960-01, Vol.5 (4), p.453-459
1. Verfasser: Ekins, R.P.
Format: Artikel
Sprache:eng
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Zusammenfassung:A new method for the determination of thyroxine in blood is described. It relies upon the quantitative dependence of the distribution of thyroxine between albumin and thyroxine-binding protein when exogenous 131I-labelled thyroxine is added to serum in vitro. Preliminary results suggest an accuracy in the estimate of the hormone of about 5–10%. Results in a group of patients whose plasma P.B.I, levels were also determined are given and shown to be similar.
ISSN:0009-8981
1873-3492
DOI:10.1016/0009-8981(60)90051-6