Acute Effects of Guanethidine on Myocardial Contractility and Catecholamine Levels.

Acute Effects of Guanethidine on Myocardial Contractility and Catecholamine Levels.

Summary Guanethidine elicits a period of augmented myocardial contractility. Significant decrements in ventricle and aorta norepinephrine content are caused by the drug. With isolated hearts, the agent releases norepinephrine.

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Bibliographische Detailangaben
Veröffentlicht in:Experimental biology and medicine (Maywood, N.J.) N.J.), 1961-02, Vol.106 (2), p.259-262
Hauptverfasser: Butterfield, J. L., Richardson, J. A.
Format: Artikel
Sprache:eng
Schlagworte:
Amidines - pharmacology
Antihypertensive Agents - pharmacology
Catecholamines - metabolism
Guanethidine
Heart - pharmacology
Muscle Contraction
Myocardium - metabolism
Old Medline
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Zusammenfassung:Summary Guanethidine elicits a period of augmented myocardial contractility. Significant decrements in ventricle and aorta norepinephrine content are caused by the drug. With isolated hearts, the agent releases norepinephrine.
ISSN:0037-9727
1535-3702
1535-3699
DOI:10.3181/00379727-106-26303