Implantation and embryonic survival in rats treated with amaranth during gestation

Samples of amaranth obtained from three manufacturers were administered to rats by gavage or mixed in a semi-synthetic diet, to provide in each case dosage levels of 0, 15, 30, 100 or 200 mg/kg body weight/day, from day 1 to 19 of pregnancy (day 1 being the day sperm were found in vaginal smears). D...

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Veröffentlicht in:	Food and cosmetics toxicology 1974-08, Vol.12 (4), p.507-510
Hauptverfasser:	Khera, K.S., Przybylski, W., McKinley, W.P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amaranth Dye - administration & dosage Amaranth Dye - pharmacology Animals Azo Compounds - pharmacology Body Weight - drug effects Diet Embryo Implantation - drug effects Embryo, Mammalian - drug effects Female Gestational Age Intubation, Gastrointestinal Pregnancy Rats
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Zusammenfassung:	Samples of amaranth obtained from three manufacturers were administered to rats by gavage or mixed in a semi-synthetic diet, to provide in each case dosage levels of 0, 15, 30, 100 or 200 mg/kg body weight/day, from day 1 to 19 of pregnancy (day 1 being the day sperm were found in vaginal smears). Dams were killed on day 20 of gestation. Prenatal values for corpora lutea, live foetuses, deciduomas (suggestive of early embryonic death or resorption), dead foetuses and foetal weight gave no evidence of any amaranth-related deleterious effect on implantation or embryonic survival.
ISSN:	0015-6264
DOI:	10.1016/0015-6264(74)90064-9